Blocked by Curcumin
Curcumin
activates the Switch-off mechanism to decrease phosphorylase kinase (PhK). The
side effects of the body wound healing reaction to injury are reduced. The skin
then returns to its normal state. The injury-induced pathways are depicted below:
Curcumin, the active ingredients in YoungAlways Skintech, is a natural
inhibitor of the enzyme, phosphorylase kinase(PhK). This enzymes is involved in
providing energy (ATP) from the breakdown of glycogen to energize many cellular
process. Frequently, these inflammatory pathways lead to unsightly skin appearance,
such as redness, scaling, pigmentation and scarring. By inhibiting phosphorylase
kinase activity with curcumin gel, these unsightly skin change are improved. |
Rejuvernate your Skin,
Young Always!
In normal individuals, after the wound is healed, a feed-back, switch-off mechanism
results in reduced PhK activity. In psoriasis, for example, the switch-off mechanism
for PhK is not present due to a Type II cAMP protein kinase linked to a defective
gene on the distal end (17q) of the 17th chromosome, resulting in persistently
elevated PHK activity (Heng MCY et al. Br J Dermatol 2000; 143: 937-949).
The persistently high levels of PhK in the skin result in rapid epidermal turnover
leading to defective barrier function. As a result, skin becomes permeable to
allergens and bacteria. Curcumin gel slows rapid epidermal turnover, and returns
the barrier function to normal. For more information, please access www.PsoriaInfo.org.
Studies have shown the major defect in psoriasis is loss of normal epidermal
barrier. Curcumin, by decreasing PhK levels, slows down the epidermal turnover
from once every 4 days to once every 60 days, thus normalizing the epidermal barrier,
and helping to return the skin to its normal appearance (Heng MCY et al. Br J
Dermatol 2000; 143: 937-949).
YoungAlway Skintech is specially formulated for use in inflamed skin conditions.
The use of curcumin gel helps to improve skin appearance and texture, with reduced
hyperpigmentation and scarring.
Curcumin gel also helps unplug skin pores, so that the pores decrease in size.
It may be used during the day, or in the evening. Daily use under make-up, sunscreen,
or moisturizers helps to decrease the comedogenic effects of these products. YoungAlways
Skintech may also be used to help reverse early scarring in inflamed skin.
In pre-deposed individuals, untreated scars remain thick and hyperpigmented.
Using YoungAlways curcumin gel on early surgical scars, and scars due to injury,
may improve their appearance.
In sun-damaged skin, curcumin gel helps improve the texture of the skin and
decrease the appearance of wrinkles, pigmentation, and redness. Using YoungAlways
on sun-burned skin, may decrease pain, sensitivity, and reduce long-term photo-damage.
Excessive and repeated ultraviolet light exposure to the skin results in injury-induced
inflammatory response. This leads to redness, pigmentation, wrinkling of the skin,
and formation of pre-cancerous and cancerous changes to skin cells. Curcumin gel,
by blocking the inflammatory reponse, helps to slow down these changes.
Directions: wash the skin with gentel soap and water. Pat dry with a towel.
If your skin is think and scaly, you may apply a layer of rubbing alcohol prior
to applying YoungAlways Skintech. However if the skin is cracked, dry, sun-damaged,
irriated or inflamed, you may dampen the skin with water instead, before application.
Use a clean Q-tip to transfer a small dab of YoungAlways Skintech onto the
skin. Do not re-dip, so as not to transfer bacteria from the skin back to the
jar. While the skin is still damp, massage a thin layer of gel quickly, yet thoroughly,
over the skin before it dries, spreading it out as far as it will go. A generous
application is not necessary. If YoungAlways stains the skin yellow, feels sticky
or appear flaky, too much has been applied. You may use sunscreen, moisturizer
or makeup over the YoungAlways layer once it is dry. Keep jar tightly closed to
prevent from drying out. Store in a cool, dry place. WARNING Do not use Youngalway
Skintech on eyes or mucous membranes. Do not use on open wounds. Do not take by
mouth. For external use only. May cause temporary stinging. Keep out of reach
of children. This infomation is not intended for use in self-diagnosis, or substitution
for medical consultation.
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